NF-kappa-B activation unveils the presence of inflammatory hotspots in human gut xenografts.

The single-epithelial cell layer of the gut mucosa serves as an essential barrier between the host and luminal microflora and plays a major role in innate immunity against invading pathogens. Nuclear factor kB (NF-κB), a central component of the cellular signaling machinery, regulates immune respons...

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Bibliographic Details
Main Authors: Einat Nissim-Eliraz, Eilam Nir, Noga Marsiano, Simcha Yagel, Nahum Y Shpigel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0243010&type=printable
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