A 90-Day Oral Toxicological Evaluation of the Methylurate Purine Alkaloid Theacrine

A 90-day repeated-dose oral toxicological evaluation was conducted according to GLP and OECD guidelines on the methylurate purine alkaloid theacrine, which is found naturally in certain plants. Four groups of Hsd.Brl.Han Wistar rats (ten/sex/group) were administered theacrine by gavage doses of 0 (v...

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Bibliographic Details
Main Authors: Amy Clewell, Gábor Hirka, Róbert Glávits, Philip A. Palmer, John R. Endres, Timothy S. Murbach, Tennille Marx, Ilona Pasics Szakonyiné
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2016/6206859
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