Synthesis and Characterization of 6-Carbamoyl-1,2-dihydropurines
The aromatic amines react readily with (Z)-N-(2-amino-1,2-dicyanovinyl)formimidate (4) to give the amidines (5a-b), which cyclize in the presence of DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) to give the corresponding 2-(5-Amino-1-phenyl-1H-imidazol-4-yl)-2-iminoacetonitrile (6a-b), which can be isola...
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2007/874758 |
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| author | Asieh Yahyazadeh Fatemah Hossaini |
| author_facet | Asieh Yahyazadeh Fatemah Hossaini |
| author_sort | Asieh Yahyazadeh |
| collection | DOAJ |
| description | The aromatic amines react readily with (Z)-N-(2-amino-1,2-dicyanovinyl)formimidate (4) to give the amidines (5a-b), which cyclize in the presence of DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) to give the corresponding 2-(5-Amino-1-phenyl-1H-imidazol-4-yl)-2-iminoacetonitrile (6a-b), which can be isolated. In the presence of aldehyde the formimidoylimidazole lead to novel 6-carbamoyl-1,2-dihydropurines (8a-b). All compounds have been fully characterized by spectroscopic data. |
| format | Article |
| id | doaj-art-55b557c73a6844dc973796d2d6702f71 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-55b557c73a6844dc973796d2d6702f712025-02-03T01:09:41ZengWileyE-Journal of Chemistry0973-49452090-98102007-01-014337638010.1155/2007/874758Synthesis and Characterization of 6-Carbamoyl-1,2-dihydropurinesAsieh Yahyazadeh0Fatemah Hossaini1Department of Chemistry, University of Guilan, P.O. Box 1914, Rasht, IranDepartment of Chemistry, University of Guilan, P.O. Box 1914, Rasht, IranThe aromatic amines react readily with (Z)-N-(2-amino-1,2-dicyanovinyl)formimidate (4) to give the amidines (5a-b), which cyclize in the presence of DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) to give the corresponding 2-(5-Amino-1-phenyl-1H-imidazol-4-yl)-2-iminoacetonitrile (6a-b), which can be isolated. In the presence of aldehyde the formimidoylimidazole lead to novel 6-carbamoyl-1,2-dihydropurines (8a-b). All compounds have been fully characterized by spectroscopic data.http://dx.doi.org/10.1155/2007/874758 |
| spellingShingle | Asieh Yahyazadeh Fatemah Hossaini Synthesis and Characterization of 6-Carbamoyl-1,2-dihydropurines E-Journal of Chemistry |
| title | Synthesis and Characterization of 6-Carbamoyl-1,2-dihydropurines |
| title_full | Synthesis and Characterization of 6-Carbamoyl-1,2-dihydropurines |
| title_fullStr | Synthesis and Characterization of 6-Carbamoyl-1,2-dihydropurines |
| title_full_unstemmed | Synthesis and Characterization of 6-Carbamoyl-1,2-dihydropurines |
| title_short | Synthesis and Characterization of 6-Carbamoyl-1,2-dihydropurines |
| title_sort | synthesis and characterization of 6 carbamoyl 1 2 dihydropurines |
| url | http://dx.doi.org/10.1155/2007/874758 |
| work_keys_str_mv | AT asiehyahyazadeh synthesisandcharacterizationof6carbamoyl12dihydropurines AT fatemahhossaini synthesisandcharacterizationof6carbamoyl12dihydropurines |