Synthesis and Characterization of 6-Carbamoyl-1,2-dihydropurines
The aromatic amines react readily with (Z)-N-(2-amino-1,2-dicyanovinyl)formimidate (4) to give the amidines (5a-b), which cyclize in the presence of DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) to give the corresponding 2-(5-Amino-1-phenyl-1H-imidazol-4-yl)-2-iminoacetonitrile (6a-b), which can be isola...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2007-01-01
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Series: | E-Journal of Chemistry |
Online Access: | http://dx.doi.org/10.1155/2007/874758 |
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