IQGAP Family Members in Yeast, Dictyostelium, and Mammalian Cells

IQGAPs are a family of scaffolding proteins with multiple domains, named for the IQ motifs and GTPase activating protein (GAP) related domains. Despite their GAP homology, IQGAP proteins act as effectors for GTP-bound GTPases of the Ras superfamily and do not stimulate GTP hydrolysis. IQGAPs are fou...

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Bibliographic Details
Main Author: Katie B. Shannon
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2012/894817
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