Studies on Synthesis of Pyrimidine Derivatives and their Pharmacological Evaluation

1,3,4-Oxadiazoles were associated with broad spectrum of biological activities including antituberculosis, anticonvulsant, anti-inflammatory, insecticidal, antifungal, analgesic and antitumor properties. Morpholine derivatives find their wide spectrum of antimicrobial activity and exhibit anthelmint...

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Main Authors: T. A. Naik, K. H. Chikhalia
Format: Article
Language:English
Published: Wiley 2007-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2007/507590
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author T. A. Naik
K. H. Chikhalia
author_facet T. A. Naik
K. H. Chikhalia
author_sort T. A. Naik
collection DOAJ
description 1,3,4-Oxadiazoles were associated with broad spectrum of biological activities including antituberculosis, anticonvulsant, anti-inflammatory, insecticidal, antifungal, analgesic and antitumor properties. Morpholine derivatives find their wide spectrum of antimicrobial activity and exhibit anthelmintic, bactericidal and insecticidal activity. Pyrimidine derivatives are also reported to possess antibacterial, antimicrobial, antifungal, anticancer and anticonvulsant activities. Encouraged by this observations we decided to synthesised novel pyrimidine derivatives.
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institution Kabale University
issn 0973-4945
2090-9810
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publisher Wiley
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spelling doaj-art-559f0184a12f49b4a0afd2671f64cad02025-02-03T01:01:09ZengWileyE-Journal of Chemistry0973-49452090-98102007-01-0141606610.1155/2007/507590Studies on Synthesis of Pyrimidine Derivatives and their Pharmacological EvaluationT. A. Naik0K. H. Chikhalia1Department of chemistry, Veer Narmad South Gujarat University, Surat-395 007, Gujarat, IndiaDepartment of chemistry, Veer Narmad South Gujarat University, Surat-395 007, Gujarat, India1,3,4-Oxadiazoles were associated with broad spectrum of biological activities including antituberculosis, anticonvulsant, anti-inflammatory, insecticidal, antifungal, analgesic and antitumor properties. Morpholine derivatives find their wide spectrum of antimicrobial activity and exhibit anthelmintic, bactericidal and insecticidal activity. Pyrimidine derivatives are also reported to possess antibacterial, antimicrobial, antifungal, anticancer and anticonvulsant activities. Encouraged by this observations we decided to synthesised novel pyrimidine derivatives.http://dx.doi.org/10.1155/2007/507590
spellingShingle T. A. Naik
K. H. Chikhalia
Studies on Synthesis of Pyrimidine Derivatives and their Pharmacological Evaluation
E-Journal of Chemistry
title Studies on Synthesis of Pyrimidine Derivatives and their Pharmacological Evaluation
title_full Studies on Synthesis of Pyrimidine Derivatives and their Pharmacological Evaluation
title_fullStr Studies on Synthesis of Pyrimidine Derivatives and their Pharmacological Evaluation
title_full_unstemmed Studies on Synthesis of Pyrimidine Derivatives and their Pharmacological Evaluation
title_short Studies on Synthesis of Pyrimidine Derivatives and their Pharmacological Evaluation
title_sort studies on synthesis of pyrimidine derivatives and their pharmacological evaluation
url http://dx.doi.org/10.1155/2007/507590
work_keys_str_mv AT tanaik studiesonsynthesisofpyrimidinederivativesandtheirpharmacologicalevaluation
AT khchikhalia studiesonsynthesisofpyrimidinederivativesandtheirpharmacologicalevaluation