Alterations in BCR heavy chain CDR3 repertoire characteristics in pediatric mycoplasma pneumoniae infection

Alterations in BCR heavy chain CDR3 repertoire characteristics in pediatric mycoplasma pneumoniae infection

IntroductionMycoplasma pneumoniae (MP) infection is a leading cause of pediatric pneumonia, triggering a complex immune response in which B cells play a critical role. This study aimed to analyze B cell receptor (BCR) heavy chain CDR3 repertoires in MP patients.MethodsClinical data from 202 children...

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Main Authors: Yanfei Chen, Yi Yuan, Xingzhu Liu, Bin Li, Lijuan Meng, Ying Xiao, Zhongjian Su, Linfei Han, Hong Li, Lili Deng, Jun Li, Caixia Ye, Xing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Mycoplasma pneumoniae
B cell receptor
CDR3 repertoire
flow cytometry
clonal expansion
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1573511/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1573511/full

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