Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae

Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae

IntroductionThe capsular polysaccharide (CPS) of pathogenic bacteria is a critical virulence factor, often evading phagocytosis by host immune cells, while also interfering with the contact of the pathogen with host cells and contributing to biofilm formation. Klebsiella pneumoniae, a Gram-negative...

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Bibliographic Details
Main Authors: Lisa Zierke, Rodi Mourad, Thomas P. Kohler, Mathias Müsken, Sven Hammerschmidt
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Microbiology
Subjects:
Klebsiella pneumoniae
capsule
adherence
phagocytosis
infection
Galleria mellonella
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1450984/full
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