A randomized, placebo-controlled, cross-over trial of ketamine in Rett syndrome

A randomized, placebo-controlled, cross-over trial of ketamine in Rett syndrome

Abstract Background Preclinical studies and anecdotal case reports support the potential therapeutic benefit of low-dose oral ketamine as a treatment of clinical symptoms in Rett syndrome (RTT); however, no controlled studies have been conducted in RTT to evaluate safety, tolerability and efficacy....

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Bibliographic Details
Main Authors: Kathleen Campbell, Jeffrey L. Neul, David N. Lieberman, Elizabeth Berry-Kravis, Tim A. Benke, Cary Fu, Alan Percy, Bernhard Suter, David Morris, Randall L. Carpenter, Eric D. Marsh, Jana von Hehn
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Rett syndrome
Ketamine
Clinical trial
Electroencephalography
Online Access:https://doi.org/10.1186/s11689-025-09591-y
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