Insulin Edema Syndrome due to Rapid Glucose Correction in a Diabetic Patient

Edema resulting from the initiation of insulin therapy or intensification of glycemic control is a rare and under-recognized complication. In this report, we present a case of a 46-year-old patient with insulin-dependent diabetes mellitus (IDDM) who avoided insulin treatment due to associated periph...

Full description

Saved in:
Bibliographic Details
Main Authors: Siham M. Hussien, Hasan Imanli, Dena H. Tran, Robert D. Chow, Aseem Sood
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2022/3027530
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832549230504312832
author Siham M. Hussien
Hasan Imanli
Dena H. Tran
Robert D. Chow
Aseem Sood
author_facet Siham M. Hussien
Hasan Imanli
Dena H. Tran
Robert D. Chow
Aseem Sood
author_sort Siham M. Hussien
collection DOAJ
description Edema resulting from the initiation of insulin therapy or intensification of glycemic control is a rare and under-recognized complication. In this report, we present a case of a 46-year-old patient with insulin-dependent diabetes mellitus (IDDM) who avoided insulin treatment due to associated peripheral edema. Though rare, this phenomenon is typically seen in patients with elevated glucose levels who are initiated on insulin treatment, resulting in rapid correction and tight control of glucose levels. The diagnosis of insulin-induced edema is made after other causes of acute edema are ruled out. Furthermore, in this case report, we will also discuss the postulated mechanisms for the edema-causing property of insulin.
format Article
id doaj-art-54feaace598b48ccb34c20db76e39e7c
institution Kabale University
issn 1687-9635
language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-54feaace598b48ccb34c20db76e39e7c2025-02-03T06:11:51ZengWileyCase Reports in Medicine1687-96352022-01-01202210.1155/2022/3027530Insulin Edema Syndrome due to Rapid Glucose Correction in a Diabetic PatientSiham M. Hussien0Hasan Imanli1Dena H. Tran2Robert D. Chow3Aseem Sood4Department of MedicineDepartment of MedicineDepartment of MedicineDepartment of MedicineDepartment of MedicineEdema resulting from the initiation of insulin therapy or intensification of glycemic control is a rare and under-recognized complication. In this report, we present a case of a 46-year-old patient with insulin-dependent diabetes mellitus (IDDM) who avoided insulin treatment due to associated peripheral edema. Though rare, this phenomenon is typically seen in patients with elevated glucose levels who are initiated on insulin treatment, resulting in rapid correction and tight control of glucose levels. The diagnosis of insulin-induced edema is made after other causes of acute edema are ruled out. Furthermore, in this case report, we will also discuss the postulated mechanisms for the edema-causing property of insulin.http://dx.doi.org/10.1155/2022/3027530
spellingShingle Siham M. Hussien
Hasan Imanli
Dena H. Tran
Robert D. Chow
Aseem Sood
Insulin Edema Syndrome due to Rapid Glucose Correction in a Diabetic Patient
Case Reports in Medicine
title Insulin Edema Syndrome due to Rapid Glucose Correction in a Diabetic Patient
title_full Insulin Edema Syndrome due to Rapid Glucose Correction in a Diabetic Patient
title_fullStr Insulin Edema Syndrome due to Rapid Glucose Correction in a Diabetic Patient
title_full_unstemmed Insulin Edema Syndrome due to Rapid Glucose Correction in a Diabetic Patient
title_short Insulin Edema Syndrome due to Rapid Glucose Correction in a Diabetic Patient
title_sort insulin edema syndrome due to rapid glucose correction in a diabetic patient
url http://dx.doi.org/10.1155/2022/3027530
work_keys_str_mv AT sihammhussien insulinedemasyndromeduetorapidglucosecorrectioninadiabeticpatient
AT hasanimanli insulinedemasyndromeduetorapidglucosecorrectioninadiabeticpatient
AT denahtran insulinedemasyndromeduetorapidglucosecorrectioninadiabeticpatient
AT robertdchow insulinedemasyndromeduetorapidglucosecorrectioninadiabeticpatient
AT aseemsood insulinedemasyndromeduetorapidglucosecorrectioninadiabeticpatient