Granulocytic Sarcoma of Parotid Gland in a 4-Year-Old Child with Subleukemic AML: A Diagnostic Challenge!

A 4-year-old male child presented to our outpatient department with large swelling in the parotid region. Routine investigations were all within normal limits, and evaluation of complete blood count was normal except for anaemia. Excisional biopsy as a therapeutic diagnosis was done. Microscopic exa...

Full description

Saved in:
Bibliographic Details
Main Authors: Yashwant Ingale, Tushar Patil, Priyanka Chaudhari, Samapika Routray, Manoj Agrawal
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2013/321289
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832556066124070912
author Yashwant Ingale
Tushar Patil
Priyanka Chaudhari
Samapika Routray
Manoj Agrawal
author_facet Yashwant Ingale
Tushar Patil
Priyanka Chaudhari
Samapika Routray
Manoj Agrawal
author_sort Yashwant Ingale
collection DOAJ
description A 4-year-old male child presented to our outpatient department with large swelling in the parotid region. Routine investigations were all within normal limits, and evaluation of complete blood count was normal except for anaemia. Excisional biopsy as a therapeutic diagnosis was done. Microscopic examination showed monomorphic population of discohesive, hyperchromatic small round cells having high N : C ratio, coarse chromatin, conspicuous nucleoli, and sometimes angulated nuclei lying in sheets. Immunohistochemistry was done to rule out possible differential diagnosis. Fine needle aspiration from the swelling showed predominant population of blast cells. Myeloperoxidase and PBO were strongly positive, and diagnosis of granulocytic sarcoma was confirmed.
format Article
id doaj-art-54925b8ae2ee482e93303c5e31db1528
institution Kabale University
issn 2090-6765
2090-6773
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Case Reports in Otolaryngology
spelling doaj-art-54925b8ae2ee482e93303c5e31db15282025-02-03T05:46:27ZengWileyCase Reports in Otolaryngology2090-67652090-67732013-01-01201310.1155/2013/321289321289Granulocytic Sarcoma of Parotid Gland in a 4-Year-Old Child with Subleukemic AML: A Diagnostic Challenge!Yashwant Ingale0Tushar Patil1Priyanka Chaudhari2Samapika Routray3Manoj Agrawal4Department of Dentistry, Yashwantrao Chavan Memorial Hospital, Pimpri, Pune 411018, IndiaDepartment of Pathology, Yashwantrao Chavan Memorial Hospital, Pimpri, Pune 411018, IndiaDepartment of Pathology, Yashwantrao Chavan Memorial Hospital, Pimpri, Pune 411018, IndiaDepartment of Oral Pathology & Microbiology, Institute of Dental Sciences, SOA University, Bhubaneswar, Odisha 751003, IndiaOral & Maxillofacial Surgeon, Yashwantrao Chavan Memorial Hospital, Pimpri, Pune 411018, IndiaA 4-year-old male child presented to our outpatient department with large swelling in the parotid region. Routine investigations were all within normal limits, and evaluation of complete blood count was normal except for anaemia. Excisional biopsy as a therapeutic diagnosis was done. Microscopic examination showed monomorphic population of discohesive, hyperchromatic small round cells having high N : C ratio, coarse chromatin, conspicuous nucleoli, and sometimes angulated nuclei lying in sheets. Immunohistochemistry was done to rule out possible differential diagnosis. Fine needle aspiration from the swelling showed predominant population of blast cells. Myeloperoxidase and PBO were strongly positive, and diagnosis of granulocytic sarcoma was confirmed.http://dx.doi.org/10.1155/2013/321289
spellingShingle Yashwant Ingale
Tushar Patil
Priyanka Chaudhari
Samapika Routray
Manoj Agrawal
Granulocytic Sarcoma of Parotid Gland in a 4-Year-Old Child with Subleukemic AML: A Diagnostic Challenge!
Case Reports in Otolaryngology
title Granulocytic Sarcoma of Parotid Gland in a 4-Year-Old Child with Subleukemic AML: A Diagnostic Challenge!
title_full Granulocytic Sarcoma of Parotid Gland in a 4-Year-Old Child with Subleukemic AML: A Diagnostic Challenge!
title_fullStr Granulocytic Sarcoma of Parotid Gland in a 4-Year-Old Child with Subleukemic AML: A Diagnostic Challenge!
title_full_unstemmed Granulocytic Sarcoma of Parotid Gland in a 4-Year-Old Child with Subleukemic AML: A Diagnostic Challenge!
title_short Granulocytic Sarcoma of Parotid Gland in a 4-Year-Old Child with Subleukemic AML: A Diagnostic Challenge!
title_sort granulocytic sarcoma of parotid gland in a 4 year old child with subleukemic aml a diagnostic challenge
url http://dx.doi.org/10.1155/2013/321289
work_keys_str_mv AT yashwantingale granulocyticsarcomaofparotidglandina4yearoldchildwithsubleukemicamladiagnosticchallenge
AT tusharpatil granulocyticsarcomaofparotidglandina4yearoldchildwithsubleukemicamladiagnosticchallenge
AT priyankachaudhari granulocyticsarcomaofparotidglandina4yearoldchildwithsubleukemicamladiagnosticchallenge
AT samapikaroutray granulocyticsarcomaofparotidglandina4yearoldchildwithsubleukemicamladiagnosticchallenge
AT manojagrawal granulocyticsarcomaofparotidglandina4yearoldchildwithsubleukemicamladiagnosticchallenge