Single-cell Profiling of Intrahepatic Immune Cells Reveals an Expansion of Tissue-resident Cytotoxic CD4+ T Lymphocyte Subset Associated With Pathogenesis of Alcoholic-associated Liver DiseasesSummary

Background & Aims: The immunological mechanisms underpinning the pathogenesis of alcoholic-associated liver disease (ALD) remain incompletely elucidated. This study aims to explore the transcriptomic profiles of hepatic immune cells in ALD compared with healthy individuals and those with met...

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Main Authors: Chao Gao, Shiguan Wang, Xiaoyu Xie, Pierluigi Ramadori, Xinying Li, Xiaoyu Liu, Xue Ding, Jinyuan Liang, Bowen Xu, Yawei Feng, Xueying Tan, Haoran Wang, Yan Zhang, Haiyan Zhang, Tingguo Zhang, Ping Mi, Shiyang Li, Cuijuan Zhang, Detian Yuan, Mathias Heikenwalder, Peng Zhang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X24001668
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