Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine

Inflammatory arthritis, such as pseudogout or otherwise referred to as calcium pyrophosphate (CPP) crystal arthritis or calcium pyrophosphate deposition (CPPD) disease, is characterized by the deposition of crystal formation and deposition in large joints. CPPD is known to affect the elderly populat...

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Main Authors: Indrit Greca, Jihad Ben Gabr, Andras Perl, Stephanie Bryant, Dan Zaccarini
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2020/3218350
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author Indrit Greca
Jihad Ben Gabr
Andras Perl
Stephanie Bryant
Dan Zaccarini
author_facet Indrit Greca
Jihad Ben Gabr
Andras Perl
Stephanie Bryant
Dan Zaccarini
author_sort Indrit Greca
collection DOAJ
description Inflammatory arthritis, such as pseudogout or otherwise referred to as calcium pyrophosphate (CPP) crystal arthritis or calcium pyrophosphate deposition (CPPD) disease, is characterized by the deposition of crystal formation and deposition in large joints. CPPD is known to affect the elderly population and commonly manifests as inflammation of knees, hips, and shoulders. CPPD disease involving the spine has been infrequently encountered in practice and rarely described in the literature. Here, we describe a case of an 80-year-old female with no known history of inflammatory arthritis who presented with left lower extremity weakness and fall, initially thought to have discitis, later confirming CPPD of the spine through biopsy and ultimately resolution of symptoms with anti-inflammatory agents. Although consisting of different clinical presentations, two other case reports have described CPPD of the spine with similar radiographic findings, to this author’s knowledge. With the radiologic similarities, this unique case serves to raise awareness in the medical community and possibly place pseudogout of the spine on the differential list when such cases are encountered. As a result, patients can be initiated on benign anti-inflammatory agents, avoiding invasive testing and unnecessary antibiotic exposure.
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spelling doaj-art-542730d8652d4914901d2ca7c63b7bda2025-02-03T00:59:43ZengWileyCase Reports in Rheumatology2090-68892090-68972020-01-01202010.1155/2020/32183503218350Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar SpineIndrit Greca0Jihad Ben Gabr1Andras Perl2Stephanie Bryant3Dan Zaccarini4SUNY Upstate University Hospital, Syracuse, NY-13210, USASUNY Upstate University Hospital, Syracuse, NY-13210, USASUNY Upstate University Hospital, Syracuse, NY-13210, USASUNY Upstate University Hospital, Syracuse, NY-13210, USASUNY Upstate University Hospital, Syracuse, NY-13210, USAInflammatory arthritis, such as pseudogout or otherwise referred to as calcium pyrophosphate (CPP) crystal arthritis or calcium pyrophosphate deposition (CPPD) disease, is characterized by the deposition of crystal formation and deposition in large joints. CPPD is known to affect the elderly population and commonly manifests as inflammation of knees, hips, and shoulders. CPPD disease involving the spine has been infrequently encountered in practice and rarely described in the literature. Here, we describe a case of an 80-year-old female with no known history of inflammatory arthritis who presented with left lower extremity weakness and fall, initially thought to have discitis, later confirming CPPD of the spine through biopsy and ultimately resolution of symptoms with anti-inflammatory agents. Although consisting of different clinical presentations, two other case reports have described CPPD of the spine with similar radiographic findings, to this author’s knowledge. With the radiologic similarities, this unique case serves to raise awareness in the medical community and possibly place pseudogout of the spine on the differential list when such cases are encountered. As a result, patients can be initiated on benign anti-inflammatory agents, avoiding invasive testing and unnecessary antibiotic exposure.http://dx.doi.org/10.1155/2020/3218350
spellingShingle Indrit Greca
Jihad Ben Gabr
Andras Perl
Stephanie Bryant
Dan Zaccarini
Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine
Case Reports in Rheumatology
title Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine
title_full Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine
title_fullStr Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine
title_full_unstemmed Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine
title_short Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine
title_sort trauma induced calcium pyrophosphate deposition disease of the lumbar spine
url http://dx.doi.org/10.1155/2020/3218350
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