Bioinformatic analyses reveal lysosomal-associated protein transmembrane 5 as a potential therapeutic target in lipotoxicity-induced injury in diabetic kidney disease

Bioinformatic analyses reveal lysosomal-associated protein transmembrane 5 as a potential therapeutic target in lipotoxicity-induced injury in diabetic kidney disease

Emerging data have revealed that damage to tubular epithelial cell is a driving force in the progression of diabetic kidney disease (DKD). However, the specific mechanisms by which lipotoxicity contributes to the injury of these cells, thereby influencing the development of DKD, are yet to be fully...

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Bibliographic Details
Main Authors: Xin Chen, Shenglong Zhu, Ciyou Huang, Jiayi Liu, Jinbang Wang, Siyuan Cui
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Renal Failure
Subjects:
Diabetic kidney disease
biomarker
lipotoxicity
LAPTM5
bioinformatics
inflammation
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2359638
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https://www.tandfonline.com/doi/10.1080/0886022X.2024.2359638

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