Efficacy and Tolerability of a New Facial 2-Mercaptonicotinoyl Glycine-Containing Depigmenting Serum Versus Hydroquinone 4% over 3-Month Treatment of Facial Melasma

Efficacy and Tolerability of a New Facial 2-Mercaptonicotinoyl Glycine-Containing Depigmenting Serum Versus Hydroquinone 4% over 3-Month Treatment of Facial Melasma

Abstract Introduction Topical treatment with hydroquinone 4% and hydroquinone-based preparations is the gold standard of care for melasma; however, it is limited by complications. 2-Mercaptonicotinoyl glycine (Melasyl™) is a new active ingredient targeting melanin synthesis without impairing the tyr...

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Main Authors: Thierry Passeron, Delphine Kerob, Guénaëlle Le Dantec, Anne-Laure Demessant-Flavigny, Alessandro R. do Nascimento, Renato Moura, Samir Salah, Mariana Feiges, Erika Fernandez, Andrew Alexis
Format: Article
Language:English
Published: Adis, Springer Healthcare 2025-06-01
Series:Dermatology and Therapy
Subjects:
2-Mercaptonicotinoyl glycine
Depigmenting serum
Hydroquinone
Melasma
Topical treatment
Online Access:https://doi.org/10.1007/s13555-025-01473-4
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https://doi.org/10.1007/s13555-025-01473-4

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