How does the tea L-theanine buffer stress and anxiety
Tea (Camellia sinensis) is widely considered to promote feelings of calming and soothing. This effect is attributed to L-theanine (L-γ-glutamylethylamide) in tea, a non-protein amino acid mainly derived from tea leaves. As a naturally occurring structural analogue of glutamate, L-theanine competes f...
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Format: | Article |
Language: | English |
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Tsinghua University Press
2022-05-01
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Series: | Food Science and Human Wellness |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453021001324 |
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author | Liwen Wang Margaret Brennan Shiming Li Hui Zhao Klaus W. Lange Charles Brennan |
author_facet | Liwen Wang Margaret Brennan Shiming Li Hui Zhao Klaus W. Lange Charles Brennan |
author_sort | Liwen Wang |
collection | DOAJ |
description | Tea (Camellia sinensis) is widely considered to promote feelings of calming and soothing. This effect is attributed to L-theanine (L-γ-glutamylethylamide) in tea, a non-protein amino acid mainly derived from tea leaves. As a naturally occurring structural analogue of glutamate, L-theanine competes for the receptors with glutamate and is able to pass the blood-brain barrier to exert its relaxation effect. This review focuses on the relaxation effect of L-theanine, including animal models and the latest human trials as well as the potential molecular mechanisms regarding neuron stem cells. The biological efficacy of dietary L-theanine in the food matrix has been further discussed in this review in relation to the physiological changes in the gastrointestinal tract and bindings of L-theanine with other food components. |
format | Article |
id | doaj-art-53d9a2e5731f491cad87d0105c28568d |
institution | Kabale University |
issn | 2213-4530 |
language | English |
publishDate | 2022-05-01 |
publisher | Tsinghua University Press |
record_format | Article |
series | Food Science and Human Wellness |
spelling | doaj-art-53d9a2e5731f491cad87d0105c28568d2025-02-02T23:24:54ZengTsinghua University PressFood Science and Human Wellness2213-45302022-05-01113467475How does the tea L-theanine buffer stress and anxietyLiwen Wang0Margaret Brennan1Shiming Li2Hui Zhao3Klaus W. Lange4Charles Brennan5College of Food Science and Technology, Hebei Agricultural University, Baoding 071001, ChinaDepartment of Wine, Food and Molecular Biosciences, Lincoln University, Christchurch 7647, New ZealandHubei Key Laboratory of EFGIR, Huanggang Normal University, Huanggang 438000, China; Correspondence to: RFH076, PO Box 85084, Lincoln University, Lincoln 7647, Christchurch, New ZealandTianjin Key Laboratory of Food and Biotechnology, University of Commerce, Tianjin 300134, ChinaDepartment of Experimental Psychology, University of Regensburg, Regensburg 93040, GermanyDepartment of Wine, Food and Molecular Biosciences, Lincoln University, Christchurch 7647, New Zealand; School of Science, RMIT, Melbourne, VIC 3000, Australia; Correspondence to: Department of Food Science School of Environmental and Biological Sciences Rutgers, The State University of New Jersey 65 Dudley Road, New Brunswick, NJ 08901-8520 Fax: 732-932-6776Tea (Camellia sinensis) is widely considered to promote feelings of calming and soothing. This effect is attributed to L-theanine (L-γ-glutamylethylamide) in tea, a non-protein amino acid mainly derived from tea leaves. As a naturally occurring structural analogue of glutamate, L-theanine competes for the receptors with glutamate and is able to pass the blood-brain barrier to exert its relaxation effect. This review focuses on the relaxation effect of L-theanine, including animal models and the latest human trials as well as the potential molecular mechanisms regarding neuron stem cells. The biological efficacy of dietary L-theanine in the food matrix has been further discussed in this review in relation to the physiological changes in the gastrointestinal tract and bindings of L-theanine with other food components.http://www.sciencedirect.com/science/article/pii/S2213453021001324L-theanineRelaxationStressAnxietyFood matrix |
spellingShingle | Liwen Wang Margaret Brennan Shiming Li Hui Zhao Klaus W. Lange Charles Brennan How does the tea L-theanine buffer stress and anxiety Food Science and Human Wellness L-theanine Relaxation Stress Anxiety Food matrix |
title | How does the tea L-theanine buffer stress and anxiety |
title_full | How does the tea L-theanine buffer stress and anxiety |
title_fullStr | How does the tea L-theanine buffer stress and anxiety |
title_full_unstemmed | How does the tea L-theanine buffer stress and anxiety |
title_short | How does the tea L-theanine buffer stress and anxiety |
title_sort | how does the tea l theanine buffer stress and anxiety |
topic | L-theanine Relaxation Stress Anxiety Food matrix |
url | http://www.sciencedirect.com/science/article/pii/S2213453021001324 |
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