Evaluating the potential of assembler-binner combinations in recovering low-abundance and strain-resolved genomes from human metagenomes
Human-associated microbial communities are a complex mixture of bacterial species and diverse strains prevalent at varying abundances. Due to the inherent limitations of metagenomic assemblers and genome binning tools in recovering low-abundance species (<1 %) and strains, we lack comprehensive i...
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Main Authors: | Hajra Qayyum, Muhammad Sarfraz Talib, Amjad Ali, Masood Ur Rehman Kayani |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025003184 |
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