NEoAdjuvant radiohormonal therapy versus standard of care for oligometastatic prostate cancer (NEAR-TOP): study protocol of a multicenter, open-label, randomised controlled trial

NEoAdjuvant radiohormonal therapy versus standard of care for oligometastatic prostate cancer (NEAR-TOP): study protocol of a multicenter, open-label, randomised controlled trial

Abstract Background Metastatic prostate cancer is commonly treated with androgen deprivation therapy (ADT) and chemotherapy, which often leads to treatment resistance and disease progression with limited effective interventions. Recent advances in robotic surgery and precision radiotherapy have prom...

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Main Authors: Zhiguo Fan, Duocai Li, Shi Yan, Xianzhi Zhao, Lei Yin, Weidong Xu, Ye Wang, Huojun Zhang, Yifan Chang, Shancheng Ren
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cancer
Subjects:
Oligometastatic prostate cancer
Preoperative radiotherapy
Robotic-assisted
Radical prostatectomy
Endocrine therapy
Prognosis
Online Access:https://doi.org/10.1186/s12885-024-13201-w
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https://doi.org/10.1186/s12885-024-13201-w

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