Activation of KATP channels in pain modulation: a systematic review of preclinical studies

ObjectiveTo systematically review the involvement of KATP channel activation in pain modulation in preclinical studies.BackgroundKATP channels are expressed at several levels in the spinal and trigeminal pain pathways, where they seem to modulate nociceptive transmission.MethodsPubMed and Embase dat...

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Bibliographic Details
Main Authors: Signe Schønning Beich, Lili Kokoti, Mohammad Al-Mahdi Al-Karagholi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1444270/full
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