TSG6 affects anti cancer drug resistance and angiogenesis in 3D spheroid model of canine mammary gland tumor cells

TSG6 affects anti cancer drug resistance and angiogenesis in 3D spheroid model of canine mammary gland tumor cells

Abstract TSG6 (Tumor necrosis factor stimulated gene-6) plays a critical role in modulating the tumor microenvironment by regulating inflammation, immune responses, and extracellular matrix remodeling. Hypoxia affects tumor growth, angiogenesis, and anti-cancer drug resistance in the tumor microenvi...

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Bibliographic Details
Main Authors: Ga-Hyun Lim, Ju-Hyun An, Jeong-Hwa Lee, Kyoung-Won Seo, Hwa-Young Youn
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Angiogenesis
Anti-cancer drug resistance
Canine mammary gland tumor
TSG6
Tumor microenvironment
Spheroid
Online Access:https://doi.org/10.1038/s41598-025-12950-3
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https://doi.org/10.1038/s41598-025-12950-3

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