MicroRNA-384 radiosensitizes human non-small cell lung cancer by impairing DNA damage response and repair signaling, which is inhibited by NF-κB

MicroRNA-384 radiosensitizes human non-small cell lung cancer by impairing DNA damage response and repair signaling, which is inhibited by NF-κB

Objective: Radiotherapy has achieved remarkable effects in treating non-small cell lung cancer (NSCLC). However, radioresistance remains the major obstacle to achieving good outcomes. This study aims at identifying potential targets for radiosensitizing NSCLC and elucidating the underlying mechanism...

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Bibliographic Details
Main Authors: Yanchen Sun, Jing Wang, Minghan Qiu, Jinlin Zhao, Fangdi Zou, Maobin Meng, Xiangli Jiang, Zhiyong Yuan, Zeyun Mi, Zhiqiang Wu
Format: Article
Language:English
Published: China Anti-Cancer Association 2024-11-01
Series:Cancer Biology & Medicine
Subjects:
radiotherapy
non-small-cell lung cancer
dna damage and repair
microrna
nf-κb
Online Access:https://www.cancerbiomed.org/content/21/11/1050
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https://www.cancerbiomed.org/content/21/11/1050

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