Alpha synuclein overexpression can drive microbiome dysbiosis in mice

Alpha synuclein overexpression can drive microbiome dysbiosis in mice

Abstract Growing evidence indicates that persons with Parkinson disease (PD), have a unique composition of indigenous gut microbes. Given the long prodromal or pre-diagnosed period, longitudinal studies of the human and rodent gut microbiome before symptomatic onset and for the duration of the disea...

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Bibliographic Details
Main Authors: Timothy R. Sampson, Zachary D Wallen, Woong-Jai Won, David G. Standaert, Haydeh Payami, Ashley S. Harms
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Metagenomics
Alpha-synuclein
Transgene
Parkinson’s disease
Gut microbiome
Age-related dysbiosis
Online Access:https://doi.org/10.1038/s41598-024-82139-7
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https://doi.org/10.1038/s41598-024-82139-7

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