Boanmycin overcomes bortezomib resistance by inducing DNA damage and endoplasmic reticulum functional impairment in multiple myeloma

Boanmycin overcomes bortezomib resistance by inducing DNA damage and endoplasmic reticulum functional impairment in multiple myeloma

Abstract Background Multiple myeloma (MM) is a hematological malignancy characterized by uncontrolled proliferation of plasma cells and is currently incurable. Despite advancements in therapeutic strategies, resistance to proteasome inhibitors, particularly bortezomib (BTZ), poses a substantial chal...

Full description

Saved in:
Bibliographic Details
Main Authors: Jin-Xing Wang, Ling Zhang, Peng-Wei Zhang, Luo-Wei Yuan, Jian Jiang, Xiao-Hui Cheng, Wei Zhu, Yong Lei, Fa-Qing Tian
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Biology Direct
Subjects:
Multiple myeloma
Boanmycin
Bortezomib resistance
Endoplasmic reticulum
Online Access:https://doi.org/10.1186/s13062-024-00590-y
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s13062-024-00590-y

Similar Items