Inhibition of neuronal necroptosis via disruption of RIPK1-RIPK3 Interactions: The role of neural stem cell-derived exosomes in spinal cord injury recovery

Inhibition of neuronal necroptosis via disruption of RIPK1-RIPK3 Interactions: The role of neural stem cell-derived exosomes in spinal cord injury recovery

Spinal cord injury (SCI) poses a significant economic and public health burden. Exosomes derived from neural stem cells (NSC-Exos) are emerging as a promising therapeutic strategy for SCI repair, overcoming several limitations associated with both autologous and allogeneic neural stem cell therapies...

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Bibliographic Details
Main Authors: Shiming Li, Guoliang Chen, Kuileung Tong, Yunshu Che, Yifan Xie, Wenxiao Shi, Anquan Huang, Yefeng Wang, Jianfeng Li, Genlong Jiao, Dacheng He, Jun Shen, Fuxin Wei, Ningning Chen
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-09-01
Series:Bioactive Materials
Subjects:
Spinal cord Injury
Neural stem cells
Exosomes
Necroptosis
Necrosomes
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25002786
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