RASGRF2 as a potential pathogenic gene mediating the progression of alcoholic hepatitis to alcohol-related cirrhosis and hepatocellular carcinoma

RASGRF2 as a potential pathogenic gene mediating the progression of alcoholic hepatitis to alcohol-related cirrhosis and hepatocellular carcinoma

Abstract Background and aims Alcoholic hepatitis (AH) and hepatocellular carcinoma (HCC) are common liver diseases. Chronic inflammation caused by AH can progress to alcoholic cirrhosis (AC) and eventually HCC. Methods This study sought to ascertain potential shared genes between AH and HCC through...

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Bibliographic Details
Main Authors: Zhengyuan Chen, Danfeng Fan, Tianyi Hang, Xiaoqing Yue
Format: Article
Language:English
Published: Springer 2025-01-01
Series:Discover Oncology
Subjects:
Alcoholic hepatitis
Hepatocellular carcinoma
Bulk transcriptome
Single-cell transcriptome
Spatial transcriptome
HepG2
Online Access:https://doi.org/10.1007/s12672-025-01853-4
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https://doi.org/10.1007/s12672-025-01853-4

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