Epicardial Ablation for Arrhythmogenic Disorders in Patients with Brugada Syndrome
Brugada syndrome (BrS) is an inherited arrhythmogenic disorder characterized by distinct electrocardiographic patterns and an increased risk of sudden cardiac death due to ventricular arrhythmias. Effective management of BrS is essential, particularly for high-risk patients with recurrent arrhythmia...
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MDPI AG
2024-12-01
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| Online Access: | https://www.mdpi.com/2227-9059/13/1/27 |
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| author | Andrea Matteucci Marco Valerio Mariani Luca Sgarra Michela Bonanni Marco Frazzetto Vincenzo Mirco La Fazia Nicola Pierucci Carlo Lavalle Claudio Pandozi Federico Nardi Furio Colivicchi |
| author_facet | Andrea Matteucci Marco Valerio Mariani Luca Sgarra Michela Bonanni Marco Frazzetto Vincenzo Mirco La Fazia Nicola Pierucci Carlo Lavalle Claudio Pandozi Federico Nardi Furio Colivicchi |
| author_sort | Andrea Matteucci |
| collection | DOAJ |
| description | Brugada syndrome (BrS) is an inherited arrhythmogenic disorder characterized by distinct electrocardiographic patterns and an increased risk of sudden cardiac death due to ventricular arrhythmias. Effective management of BrS is essential, particularly for high-risk patients with recurrent arrhythmias. While implantable cardioverter–defibrillator (ICD) is effective in terminating life-threatening arrhythmias, it does not prevent arrhythmia onset and can lead to complications such as inappropriate shocks. Epicardial ablation has emerged as a promising treatment option for patients with recurrent ventricular arrhythmias and frequent ICD interventions. This review examines the latest advancements in the management of Brugada syndrome, focusing on the role and rationale of epicardial ablation for the treatment of patients at risk of sudden cardiac death. |
| format | Article |
| id | doaj-art-52009a9c039b40c78f8225ff0bbfe4d9 |
| institution | Kabale University |
| issn | 2227-9059 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj-art-52009a9c039b40c78f8225ff0bbfe4d92025-01-24T13:23:45ZengMDPI AGBiomedicines2227-90592024-12-011312710.3390/biomedicines13010027Epicardial Ablation for Arrhythmogenic Disorders in Patients with Brugada SyndromeAndrea Matteucci0Marco Valerio Mariani1Luca Sgarra2Michela Bonanni3Marco Frazzetto4Vincenzo Mirco La Fazia5Nicola Pierucci6Carlo Lavalle7Claudio Pandozi8Federico Nardi9Furio Colivicchi10Clinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, ItalyDepartment of Cardiovascular, Respiratory, Nephrological, Aenesthesiological and Geriatric Sciences “Sapienza” University of Rome, 00185 Rome, ItalyCardiology Department, Regional General Hospital “F. Miulli”, 70021 Bari, ItalyDepartment of Experimental Medicine, Tor Vergata University, 00133 Rome, ItalyDivision of Cardiology, Harrington Heart & Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USATexas Cardiac Arrhythmia Institute, St. David’s Medical Center, Austin, TX 78705, USADepartment of Cardiovascular, Respiratory, Nephrological, Aenesthesiological and Geriatric Sciences “Sapienza” University of Rome, 00185 Rome, ItalyDepartment of Cardiovascular, Respiratory, Nephrological, Aenesthesiological and Geriatric Sciences “Sapienza” University of Rome, 00185 Rome, ItalyClinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, ItalySanto Spirito Hospital, Casale Monferrato, 15033 Alessandria, ItalyClinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, 00135 Rome, ItalyBrugada syndrome (BrS) is an inherited arrhythmogenic disorder characterized by distinct electrocardiographic patterns and an increased risk of sudden cardiac death due to ventricular arrhythmias. Effective management of BrS is essential, particularly for high-risk patients with recurrent arrhythmias. While implantable cardioverter–defibrillator (ICD) is effective in terminating life-threatening arrhythmias, it does not prevent arrhythmia onset and can lead to complications such as inappropriate shocks. Epicardial ablation has emerged as a promising treatment option for patients with recurrent ventricular arrhythmias and frequent ICD interventions. This review examines the latest advancements in the management of Brugada syndrome, focusing on the role and rationale of epicardial ablation for the treatment of patients at risk of sudden cardiac death.https://www.mdpi.com/2227-9059/13/1/27Brugada syndromeepicardial ablationsudden cardiac death |
| spellingShingle | Andrea Matteucci Marco Valerio Mariani Luca Sgarra Michela Bonanni Marco Frazzetto Vincenzo Mirco La Fazia Nicola Pierucci Carlo Lavalle Claudio Pandozi Federico Nardi Furio Colivicchi Epicardial Ablation for Arrhythmogenic Disorders in Patients with Brugada Syndrome Biomedicines Brugada syndrome epicardial ablation sudden cardiac death |
| title | Epicardial Ablation for Arrhythmogenic Disorders in Patients with Brugada Syndrome |
| title_full | Epicardial Ablation for Arrhythmogenic Disorders in Patients with Brugada Syndrome |
| title_fullStr | Epicardial Ablation for Arrhythmogenic Disorders in Patients with Brugada Syndrome |
| title_full_unstemmed | Epicardial Ablation for Arrhythmogenic Disorders in Patients with Brugada Syndrome |
| title_short | Epicardial Ablation for Arrhythmogenic Disorders in Patients with Brugada Syndrome |
| title_sort | epicardial ablation for arrhythmogenic disorders in patients with brugada syndrome |
| topic | Brugada syndrome epicardial ablation sudden cardiac death |
| url | https://www.mdpi.com/2227-9059/13/1/27 |
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