PLK1 in cancer therapy: a comprehensive review of immunomodulatory mechanisms and therapeutic opportunities

PLK1 plays a crucial role in cell cycle regulation and cancer development, and its dysregulation has been implicated in the prognosis of a variety of malignancies. The potential of PLK1 inhibitors as cancer therapeutics has been extensively investigated. However, the underlying biology and mechanism...

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Bibliographic Details
Main Authors: Weihao Wang, Rui Zhao, Yahui Wang, Liying Pan, Fang Luan, Guobin Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1602752/full
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