Astrocytic FABP5 mediates retrograde endocannabinoid transport at central synapses

Astrocytic FABP5 mediates retrograde endocannabinoid transport at central synapses

Summary: Endocannabinoids (eCBs) regulate synaptic function via cannabinoid receptors. While eCB signaling is well understood, the mechanisms underlying eCB synaptic transport are poorly characterized. Using 2-arachidonoylglycerol (2-AG)-mediated depolarization-induced suppression of inhibition (DSI...

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Bibliographic Details
Main Authors: Saida Oubraim, Mohammad Fauzan, Keith Studholme, Chris Gordon, Sherrye T. Glaser, Roh-Yu Shen, Iwao Ojima, Martin Kaczocha, Samir Haj-Dahmane
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
Subjects:
Neuroscience
Cellular neuroscience
Cell biology
Specialized functions of cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225006030
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