Lactate-associated gene MCU promotes the proliferation, migration, and invasion of pancreatic ductal adenocarcinoma

Lactate-associated gene MCU promotes the proliferation, migration, and invasion of pancreatic ductal adenocarcinoma

Abstract Background The metabolism of lactate and lactylation of proteins are believed to influence tumor development through their effects on the tumor microenvironment and immune escape mechanisms. Nevertheless, its significance in pancreatic ductal adenocarcinoma (PDAC) has yet to be fully unders...

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Bibliographic Details
Main Authors: Yuhang Chen, Fenglin Zhang, Suoyi Dai, Jiangang Zhao, Wenxun Cai, Ke Zhang, Xinghe Liao, Lianyu Chen
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cancer
Subjects:
Lactate
Pancreatic adenocarcinoma
Tumor microenvironment
Prognosis
MCU
Online Access:https://doi.org/10.1186/s12885-025-14319-1
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https://doi.org/10.1186/s12885-025-14319-1

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