Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis
The low hydrostatic pressure in the intervertebral disc plays a crucial role in maintaining the homeostasis of the disc environment, particularly in supporting the physiological functions of nucleus pulposus cells (NPCs). However, the underlying mechanisms remain poorly understood. TRPV4, a barorece...
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Main Authors: | Junxian Hu, Yibo Zhu, Zeyu Pang, Xiaoxiao Li, Huilin Zhang, Xiangwei Li, Yongjian Gao, Yiyang Wang, Pei Li, Qiang Zhou |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-01-01
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Series: | Frontiers in Medicine |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1531907/full |
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