Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis

The low hydrostatic pressure in the intervertebral disc plays a crucial role in maintaining the homeostasis of the disc environment, particularly in supporting the physiological functions of nucleus pulposus cells (NPCs). However, the underlying mechanisms remain poorly understood. TRPV4, a barorece...

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Bibliographic Details
Main Authors: Junxian Hu, Yibo Zhu, Zeyu Pang, Xiaoxiao Li, Huilin Zhang, Xiangwei Li, Yongjian Gao, Yiyang Wang, Pei Li, Qiang Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1531907/full
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