Cytometry‐based single‐cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF‐α‐induced apoptosis in vivo

Cytometry‐based single‐cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF‐α‐induced apoptosis in vivo

Abstract Understanding heterogeneous cellular behaviors in a complex tissue requires the evaluation of signaling networks at single‐cell resolution. However, probing signaling in epithelial tissues using cytometry‐based single‐cell analysis has been confounded by the necessity of single‐cell dissoci...

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Main Authors: Alan J Simmons, Amrita Banerjee, Eliot T McKinley, Cherie' R Scurrah, Charles A Herring, Leslie S Gewin, Ryota Masuzaki, Seth J Karp, Jeffrey L Franklin, Michael J Gerdes, Jonathan M Irish, Robert J Coffey, Ken S Lau
Format: Article
Language:English
Published: Springer Nature 2015-10-01
Series:Molecular Systems Biology
Subjects:
apoptosis
CyTOF
epithelial signaling
single‐cell biology
TNF
Online Access:https://doi.org/10.15252/msb.20156282
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https://doi.org/10.15252/msb.20156282

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