hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways

hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways

BackgroundBreast cancer remains a leading cause of mortality among women worldwide, with existing therapeutic options often accompanied by significant side effects and a persistent risk of disease recurrence. This highlights the need for novel drug candidates with new mechanisms of action by targeti...

Full description

Saved in:
Bibliographic Details
Main Authors: Yan Yu, Chengchun Zhu, Xiao Wang, Ying Shi, Yiping Gao, Zhiyi Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
hERG activator
antitumor mechanisms
triple negative breast cancer
ER+ breast cancer
combination therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1545300/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items