CD4+ T-cell transcription factors predict phenoconversion in idiopathic rapid eye movement sleep behavior disorder

CD4+ T-cell transcription factors predict phenoconversion in idiopathic rapid eye movement sleep behavior disorder

Aim: Early biomarkers of phenoconversion to neurodegeneration are crucial to identify individuals at high risk. In patients with idiopathic REM sleep behavior disorder (iRBD), the strongest risk factor for neurodegeneration, CD4+ T cells exhibit a peculiar transcription factor pattern.Objective: To...

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Bibliographic Details
Main Authors: Monica Pinoli, Michele Terzaghi, Franca Marino, Cristoforo Comi, Maurizio Versino, Marco Cosentino
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Future Science OA
Subjects:
biomarkers
CD4+ T lymphocytes
gene expression
Parkinson's disease
phenoconversion
transcription factors
Online Access:https://www.tandfonline.com/doi/10.1080/20565623.2024.2418821
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https://www.tandfonline.com/doi/10.1080/20565623.2024.2418821

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