Juglone-Bearing Thiopyrano[2,3-d]thiazoles Induce Apoptosis in Colorectal Adenocarcinoma Cells

Juglone-Bearing Thiopyrano[2,3-d]thiazoles Induce Apoptosis in Colorectal Adenocarcinoma Cells

Colorectal cancer is a major global health challenge, with current treatments limited by toxicity and resistance. Thiazole derivatives, known for their bioactivity, are emerging as promising alternatives. Juglone (5-hydroxy-1,4-naphthoquinone) is a naturally occurring compound with known anticancer...

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Main Authors: Yuliia Kozak, Nataliya Finiuk, Robert Czarnomysy, Agnieszka Gornowicz, Roman Pinyazhko, Andrii Lozynskyi, Serhii Holota, Olga Klyuchivska, Andriy Karkhut, Svyatoslav Polovkovych, Mykola Klishch, Rostyslav Stoika, Roman Lesyk, Krzysztof Bielawski, Anna Bielawska
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Cells
Subjects:
colorectal cancer
thiopyrano[2,3-d]thiazoles
apoptosis
proliferation
reactive oxygen species
Online Access:https://www.mdpi.com/2073-4409/14/6/465
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