Whole blood vs saline for MAP restoration in anesthetized piglets after non-traumatic hemorrhagic shock: an experimental study

Abstract In the management of hemorrhagic shock (HS), the restoration of adequate mean arterial pressure (MAP) while minimizing complications is critical. Whole blood (WB) has demonstrated physiological advantages over crystalloids such as normal saline (NS), yet direct comparisons in non-traumatic...

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Bibliographic Details
Main Authors: Fabien Coisy, Dino Tikvesa, Florian Ajavon, Augustin Gamel, Laura Grau-Mercier, Thomas Sanchez, Marylène Bacle, Jean-Yves Lefrant, Thibaut Markarian, Xavier Bobbia
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-12273-3
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