Alendronate partially rescues the periodontal defects in OIM mouse model of osteogenesis imperfecta

Alendronate partially rescues the periodontal defects in OIM mouse model of osteogenesis imperfecta

Abstract Osteogenesis imperfecta (OI) is a fairly common generalized connective disorder characterized by low bone mass, bone deformities and impaired bone quality that predisposes affected individuals to musculoskeletal fragility. Periodontal ligament (PDL)-alveolar bone and PDL-cementum entheses’...

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Bibliographic Details
Main Authors: Po-Jung Chen, Ke Wang, Meng-Hsuan Lin, Radhika Sharma, Zana Kalajzic, Mara O’Brien, Sumit Yadav
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Alendronate
Osteogenesis Imperfecta
Periodontal ligament
Sharpey’s fiber
Orthodontic tooth movement
Online Access:https://doi.org/10.1038/s41598-024-84756-8
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https://doi.org/10.1038/s41598-024-84756-8

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