Decoding Colon Cancer Heterogeneity Through Integrated miRNA–Gene Network Analysis

Decoding Colon Cancer Heterogeneity Through Integrated miRNA–Gene Network Analysis

Colon adenocarcinoma (COAD) demonstrates significant clinical heterogeneity across disease stages, gender, and age groups, posing challenges for unified therapeutic strategies. This study establishes a multi-dimensional stratification framework through integrative analysis of miRNA–gene co-expressio...

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Bibliographic Details
Main Authors: Qingcai He, Zhilong Mi, Tianyue Liu, Taihang Huang, Mao Li, Binghui Guo, Zhiming Zheng
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Mathematics
Subjects:
COAD
mutual information
miRNA
Markov Flow Entropy
co-expression network
clinical stratification
Online Access:https://www.mdpi.com/2227-7390/13/6/1020
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