Hormone replacement therapy, menopausal age and lifestyle variables are associated with better cognitive performance at follow-up but not cognition over time in older-adult women irrespective of APOE4 carrier status and co-morbidities

Hormone replacement therapy, menopausal age and lifestyle variables are associated with better cognitive performance at follow-up but not cognition over time in older-adult women irrespective of APOE4 carrier status and co-morbidities

IntroductionThe impact of Hormone Replacement Therapy (HRT) on cognitive function in postmenopausal women remains a topic of considerable debate. Although estrogen's neuroprotective effects suggest potential cognitive benefits, empirical findings are mixed.MethodsThis study uses data from the C...

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Bibliographic Details
Main Authors: Tamlyn J. Watermeyer, Sarah Gregory, Emmi Leetham, Chinedu T. Udeh-Momoh, Graciela Muniz-Terrera
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Dementia
Subjects:
hormone replacement therapy (HRT)
menopausal age
cognition
APOE4
cognitive aging
lifestyle factors
Online Access:https://www.frontiersin.org/articles/10.3389/frdem.2024.1496051/full
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https://www.frontiersin.org/articles/10.3389/frdem.2024.1496051/full

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