New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe.

Mating-type switching in Schizosaccharomyces pombe entails programmed gene conversion events regulated by DNA replication, heterochromatin, and the HP1-like chromodomain protein Swi6. The whole mechanism remains to be fully understood. Using a gene deletion library, we screened ~ 3400 mutants for de...

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Bibliographic Details
Main Authors: Takahisa Maki, Naoto Ogura, James E Haber, Hiroshi Iwasaki, Geneviève Thon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1007424&type=printable
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