Outcomes of the Paul Glaucoma Implant in Refractory Secondary Glaucoma
Mohamed M Khodeiry,1,2 Amr K Hassan,3 Abdelrahman M Elhusseiny,4 Richard K Lee,2 Mohamed S Sayed5,6 1Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, USA; 2Department of Ophthalmology, Bascom Palmer Eye Institute University of Miami Miller School of Medicine...
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Dove Medical Press
2025-01-01
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| Series: | Clinical Ophthalmology |
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| author | Khodeiry MM Hassan AK Elhusseiny AM Lee RK Sayed MS |
| author_facet | Khodeiry MM Hassan AK Elhusseiny AM Lee RK Sayed MS |
| author_sort | Khodeiry MM |
| collection | DOAJ |
| description | Mohamed M Khodeiry,1,2 Amr K Hassan,3 Abdelrahman M Elhusseiny,4 Richard K Lee,2 Mohamed S Sayed5,6 1Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, USA; 2Department of Ophthalmology, Bascom Palmer Eye Institute University of Miami Miller School of Medicine, Miami, FL, USA; 3Department of Ophthalmology, South Valley University, Qena, Egypt; 4Department of Ophthalmology, Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 5Department of Ophthalmology, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; 6Department of Ophthalmology, Moorfields Eye Hospital Dubai, Dubai Healthcare City, Dubai, United Arab EmiratesCorrespondence: Mohamed S Sayed, Department of Ophthalmology, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, Email msayed82@hotmail.comPurpose: To evaluate the efficacy and safety of the Paul Glaucoma Implant (PGI) surgery in patients with secondary glaucomas.Patients and Methods: Retrospective chart review of adult patients with medically recalcitrant secondary glaucoma who underwent PGI implantation at a single tertiary center between August 2022 and June 2023. The primary outcome measure was surgical success. Surgical success was defined as intraocular pressure (IOP) between 6 and 21 mmHg with a ≥ 20% reduction compared to baseline (with or without medications) with no need for implant removal, further glaucoma reoperation, or development of vision-threatening complications at 1 year of follow-up. The secondary outcomes were IOP, glaucoma medication numbers, visual acuity, and surgical complications.Results: Thirty eyes of 30 patients were identified. Nine patients (30%) had neovascular glaucoma, and 9 patients (30%) had silicone-oil-induced glaucoma. At 12 months postoperatively, 28 eyes (93.3%) fulfilled the success criteria. The mean IOP at 12 months was 15.2 ± 4.6 mmHg compared to the mean baseline IOP of 32.6 ± 10 mmHg (p < 0.001). A significant reduction in the mean number of glaucoma medications at 12 months compared to the baseline was observed. The complication rate was 13.3% (4 eyes), with most complications being mild and transient.Conclusion: The PGI demonstrated favorable efficacy and safety profiles in the management of medically uncontrolled secondary glaucomas.Keywords: Paul Glaucoma Implant, secondary glaucoma, intraocular pressure, tube |
| format | Article |
| id | doaj-art-4fc8ff0f38074312812c44d4bb7a5564 |
| institution | Kabale University |
| issn | 1177-5483 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj-art-4fc8ff0f38074312812c44d4bb7a55642025-01-19T16:43:00ZengDove Medical PressClinical Ophthalmology1177-54832025-01-01Volume 1916717499362Outcomes of the Paul Glaucoma Implant in Refractory Secondary GlaucomaKhodeiry MMHassan AKElhusseiny AMLee RKSayed MSMohamed M Khodeiry,1,2 Amr K Hassan,3 Abdelrahman M Elhusseiny,4 Richard K Lee,2 Mohamed S Sayed5,6 1Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, USA; 2Department of Ophthalmology, Bascom Palmer Eye Institute University of Miami Miller School of Medicine, Miami, FL, USA; 3Department of Ophthalmology, South Valley University, Qena, Egypt; 4Department of Ophthalmology, Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 5Department of Ophthalmology, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; 6Department of Ophthalmology, Moorfields Eye Hospital Dubai, Dubai Healthcare City, Dubai, United Arab EmiratesCorrespondence: Mohamed S Sayed, Department of Ophthalmology, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, Email msayed82@hotmail.comPurpose: To evaluate the efficacy and safety of the Paul Glaucoma Implant (PGI) surgery in patients with secondary glaucomas.Patients and Methods: Retrospective chart review of adult patients with medically recalcitrant secondary glaucoma who underwent PGI implantation at a single tertiary center between August 2022 and June 2023. The primary outcome measure was surgical success. Surgical success was defined as intraocular pressure (IOP) between 6 and 21 mmHg with a ≥ 20% reduction compared to baseline (with or without medications) with no need for implant removal, further glaucoma reoperation, or development of vision-threatening complications at 1 year of follow-up. The secondary outcomes were IOP, glaucoma medication numbers, visual acuity, and surgical complications.Results: Thirty eyes of 30 patients were identified. Nine patients (30%) had neovascular glaucoma, and 9 patients (30%) had silicone-oil-induced glaucoma. At 12 months postoperatively, 28 eyes (93.3%) fulfilled the success criteria. The mean IOP at 12 months was 15.2 ± 4.6 mmHg compared to the mean baseline IOP of 32.6 ± 10 mmHg (p < 0.001). A significant reduction in the mean number of glaucoma medications at 12 months compared to the baseline was observed. The complication rate was 13.3% (4 eyes), with most complications being mild and transient.Conclusion: The PGI demonstrated favorable efficacy and safety profiles in the management of medically uncontrolled secondary glaucomas.Keywords: Paul Glaucoma Implant, secondary glaucoma, intraocular pressure, tubehttps://www.dovepress.com/outcomes-of-the-paul-glaucoma-implant-in-refractory-secondary-glaucoma-peer-reviewed-fulltext-article-OPTHpaul glaucoma implantsecondary glaucomaintraocular pressuretube. |
| spellingShingle | Khodeiry MM Hassan AK Elhusseiny AM Lee RK Sayed MS Outcomes of the Paul Glaucoma Implant in Refractory Secondary Glaucoma Clinical Ophthalmology paul glaucoma implant secondary glaucoma intraocular pressure tube. |
| title | Outcomes of the Paul Glaucoma Implant in Refractory Secondary Glaucoma |
| title_full | Outcomes of the Paul Glaucoma Implant in Refractory Secondary Glaucoma |
| title_fullStr | Outcomes of the Paul Glaucoma Implant in Refractory Secondary Glaucoma |
| title_full_unstemmed | Outcomes of the Paul Glaucoma Implant in Refractory Secondary Glaucoma |
| title_short | Outcomes of the Paul Glaucoma Implant in Refractory Secondary Glaucoma |
| title_sort | outcomes of the paul glaucoma implant in refractory secondary glaucoma |
| topic | paul glaucoma implant secondary glaucoma intraocular pressure tube. |
| url | https://www.dovepress.com/outcomes-of-the-paul-glaucoma-implant-in-refractory-secondary-glaucoma-peer-reviewed-fulltext-article-OPTH |
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