Utilizing small molecules to probe and harness the proteome by pooled protein tagging with ligandable domains

Multifunctional ligand-binding domains have revolutionized cell biology by enabling the precise visualization and manipulation of fused proteins of interest through small molecule probes. Employing these domains is labor-intensive and low-throughput, limiting studies to only small subsets of protein...

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Bibliographic Details
Main Authors: Katherine E. Larrimore, Yevgeniy V. Serebrenik
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1593844/full
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