In Vivo Distribution and Therapeutic Efficacy of Radioiodine-Labeled pH-Low Insertion Peptide Variant 3 in a Mouse Model of Breast Cancer

Purpose. Extracellular acidity is a marker of highly aggressive breast cancer (BC). pH-low insertion peptides (pHLIPs) target the acidic tumor microenvironment. This study evaluates the distribution and therapeutic efficacy of radioiodine-labeled pHLIP variant 3 (Var3) in a mouse model of BC. Method...

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Bibliographic Details
Main Authors: Min Zhang, Yue Xi, Hong Chen, Wangxi Hai, Biao Li
Format: Article
Language:English
Published: SAGE Publishing 2022-01-01
Series:Molecular Imaging
Online Access:http://dx.doi.org/10.1155/2022/7456365
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