Tertiary lymphoid structures-driven immune infiltration patterns and their association with survival in neuroblastoma

Tertiary lymphoid structures-driven immune infiltration patterns and their association with survival in neuroblastoma

Background Neuroblastoma (NB), a diverse childhood cancer, needs better prognostic markers for personalized treatment. The current clinical risk stratification system does not fully explain the high heterogeneity of tumor patients. Tertiary lymphoid structures (TLS), key in tumor immunity, may serve...

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Bibliographic Details
Main Authors: Xuelian Liu, Jian Deng, Bingqing Yu, Jiaxiong Tan, Xiaoliang Lu, Minmin Zhang
Format: Article
Language:English
Published: PeerJ Inc. 2025-07-01
Series:PeerJ
Subjects:
Neuroblastoma
Tertiary lymphoid structures
Single-cell sequencing
Consensus machine learning-driven signature
Tumor microenvironment
Online Access:https://peerj.com/articles/19767.pdf
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