Analysis and risk assessment of nitrosamines in sartans using GC-MS and Monte Carlo simulation

Analysis and risk assessment of nitrosamines in sartans using GC-MS and Monte Carlo simulation

Abstract The precise detection of nitrosamines at very low levels in various substances is crucial because of their known toxicity and potential to cause genetic mutations. As a result, regulations have been established to evaluate the risk of nitrosamines and manage their presence in pharmaceutical...

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Bibliographic Details
Main Authors: Fatemeh Shomali, Zahra Talebpour, Ghazaleh Abedi, Nilufar Mousavi, Shiva Mokhtarifar, Marjan Kohandani, Vahideh Mahdavi, Noushin Adib
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Nitrosamines
Risk assessment
Quality control
Pharmaceutical
GC-MS
Online Access:https://doi.org/10.1038/s41598-025-97844-0
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