FAM98 Family Proteins Play Distinct Roles in Osteoclastogenesis and Bone Resorption

FAM98 Family Proteins Play Distinct Roles in Osteoclastogenesis and Bone Resorption

There are three FAM98 family proteins (FAM98A/B/C) in humans and mice. Their physiological functions remain largely unknown. We have previously reported that Fam98a interacts with Plekhm1 in murine osteoclasts and functions in lysosome trafficking/secretion and bone resorption in osteoclasts in vitr...

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Bibliographic Details
Main Authors: Lei Wang, Tarun Minocha, Bhaba K. Das, Mikaela D. Kunika, Aarthi Kannan, Ling Gao, Subburaman Mohan, Weirong Xing, Kottayil I. Varughese, Haibo Zhao
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biology
Subjects:
Fam98a
Fam98b
Fam98c
osteoclast
Plekhm1
lysosome
Online Access:https://www.mdpi.com/2079-7737/14/1/45
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