Urinary Uromodulin Levels and UMOD Variants in Black South Africans with Hypertension-Attributed Chronic Kidney Disease
Uromodulin, the most abundant protein in urine, is synthesized in the thick ascending loop of Henle and distal convoluted tubules. Patients with chronic kidney disease (CKD) have reduced urinary uromodulin levels secondary to tubular damage. Genome wide association studies identified significant sin...
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Main Authors: | Nolubabalo Unati Nqebelele, Caroline Dickens, Therese Dix-Peek, Raquel Duarte, Saraladevi Naicker |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
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Series: | International Journal of Nephrology |
Online Access: | http://dx.doi.org/10.1155/2019/8094049 |
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