Optimized expression of oxazolomycins in engineered Streptomyces longshengensis and their activity evaluation

Abstract Background To cope with the growing number of severe diseases and intractable pathogens, drug innovation in both chemical structures and pharmacological efficiency has become an imperative global mission. Oxazolomycins are a unique family of polyketide-polypeptide antibiotics from Streptomy...

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Bibliographic Details
Main Authors: Huiying Sun, Xiang Liu, Junyue Li, Yang Xu, Yue Li, Yuqing Tian, Huarong Tan, Jihui Zhang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Microbial Cell Factories
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Online Access:https://doi.org/10.1186/s12934-025-02726-9
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