Role of androgen receptors in sexually dimorphic phenotypes in UBE3A-dependent autism spectrum disorder

Summary: Autism spectrum disorders (ASDs) involve social, communication, and behavioral challenges. ASDs display a remarkable sex difference with a 4:1 male to female prevalence ratio; however, the underlying mechanism remains largely unknown. Using the UBE3A-overexpressing mouse model for ASD, we s...

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Bibliographic Details
Main Authors: Yuan Tian, Hui Qiao, KathrynAnn Odamah, Ling-Qiang Zhu, Heng-Ye Man
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225001282
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