HSF1 at the crossroads of chemoresistance: from current insights to future horizons in cell death mechanisms

Heat Shock Factor 1 (HSF1) is a major transcriptional factor regulating the heat shock response and has become a potential target for overcoming cancer chemoresistance. This review comprehensively examines HSF1’s role in chemoresistance and its potential as a therapeutic target in cancer. We explore...

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Bibliographic Details
Main Authors: Shruti Ghai, Rejina Shrestha, Kuo-Hui Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1500880/full
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